Ĭhemical uses The remains of the 16th century carrack Mary Rose undergoing conservation treatment with PEG in the 1980s Terra cotta warrior, showing traces of original color As of 18 December, the US CDC stated that in their jurisdiction six cases of "severe allergic reaction" had been recorded from more than 250,000 vaccinations, and of those six only one person had a "history of vaccination reactions". were treated and have recovered" from anaphylactic shock.
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As of December 2020 there is some concern that PEG could trigger allergic reaction, and in fact allergic reactions are the driver for both the United Kingdom and Canadian regulators to issue an advisory, noting that: two "individuals in the U.K. In both vaccines, the bubbles are coated with a stabilizing molecule of polyethylene glycol. Proprietary lipid technology is used for each. Both RNA vaccines consist of messenger RNA, or mRNA, encased in a bubble of oily molecules called lipids. A PEGylated lipid is used as an excipient in both the Moderna and Pfizer–BioNTech vaccines for SARS-CoV-2.PEGylation of adenoviruses for gene therapy can help prevent adverse reactions due to pre-existing adenovirus immunity.The gel with encapsulated stem cells was to be injected into the site of disease and crosslinked to create the microenvironment required for the stem cells to function. They propose using the hydrogel to address periodontitis (gum disease) by encapsulating stem cells in the gel that promote healing in the gums. An example of PEG hydrogels (see Biological uses section) in a therapeutic has been theorized by Ma et al.The possibility that PEG could be used to fuse axons is being explored by researchers studying peripheral nerve and spinal cord injury.macrogol 3350, macrogol 4000 or macrogol 6000). The name may be followed by a number which represents the average molecular weight (e.g. Macrogol (with brand names such as Laxido, GoLytely and Miralax) is the generic name for polyethylene glycol used as a laxative. Whole bowel irrigation with polyethylene glycol and added electrolytes is used for bowel preparation before surgery or colonoscopy or for children with constipation. PEG is the basis of a number of laxatives (as MiraLax, RestoraLAX, etc.).Pharmaceutical-grade PEG is used as an excipient in many pharmaceutical products, in oral, topical, and parenteral dosage forms.
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